Jeff Karp, PhD

Jeff Karp, PhD, is an acclaimed mentor and biomedical engineering professor at Harvard Medical School and MIT, a Distinguished Chair at Brigham and Women’s Hospital, and a fellow of the National Academy of Inventors. He has dedicated his research to bioinspired medical problem-solving, and his lab’s technologies have led to the formation of Thirteen companies. His technologies include a tissue glue that can seal holes inside a beating heart (inspired by snails and sandcastle worms); targeted therapy for osteoarthritis, Crohn’s disease, and brain disorders; “smart needles” that automatically stop when they reach their target; a nasal spray that neutralizes pathogens; and immunotherapy approaches to annihilate cancer. Dr. Karp lives in Brookline, Massachusetts, with his wife, children, and two Cavalier King Charle’s spaniels.

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Jeff Karp, PhD: LIT: Resensitizing Our Aliveness

The natural world has provided inspiration to poets, artists, and creatives of every ilk. And that includes inventors and innovators like Dr. Jeff Karp. In this podcast, Tami Simon speaks with the renowned biomedical engineer and founder of The Karp Lab about his new book, LIT (Life Ignition Tools): Use Nature’s Playbook to Energize Your Brain, Spark Ideas, and Ignite Action, and how you yourself can turn to the natural world as an ally for problem-solving, unexpected insight, and profound transformation on a daily basis.

Enjoy this incredibly inspiring conversation exploring: The work of the “bioinspirationalist”; how sandcastle worms inspired a new approach to vascular reconstruction in humans; the LIT state and how we can open ourselves up to limitless possibilities in any situation; the pendulum swing between “dull moments” and the times we are totally lit up; the life force within everything; the importance of changing up our routines; LEB (low energy brain); the “press pause” tool of LIT; working with intention; elevating your baseline feeling of wellness and fulfillment; viewing the world through the lens of energy transfer; how we are all contributing to evolution; the practice of cycling through your senses; appreciating our interconnectedness; creating space; aligning your thoughts and actions with your core values; turning negatives into positives; finding rituals and practices to enter into the LIT state; mining the treasures of neurodiversity; and more.

Note: This episode originally aired on Sounds True One, where these special episodes of Insights at the Edge are available to watch live on video with exclusive access to Q&As with our guests. Learn more at join.soundstrue.com.

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Just One Question | Adyashanti: Is It an Awakening If ...

Is a spiritual awakening only real if it completely rearranges your life? That’s the question Tami Simon puts to Adyashanti in this episode, and his answer digs into something a lot of seekers wrestle with: the gap between a powerful glimpse of clarity and the ongoing work of actually living from it.

Adya, the American-born teacher behind books like The End of Your World and Falling into Grace, walks through why those temporary tastes of awakening are real, even when they fade, and offers a surprisingly practical way to hold onto what they revealed without grasping at them. Then he does something rare: he tells the story of his own first major awakening, a moment he describes as feeling like a nuclear explosion going off inside him.

Here’s what we cover:

  • Why a fleeting shift still counts as a real awakening, even if it doesn’t stick
  • The two (seemingly contradictory) pieces of advice Adya gives people chasing a past peak experience
  • How the first awakening can feel like a “freebie,” while everything after asks you to participate consciously
  • Adya’s own account of the night everything fell away and the still, small voice that told him, “This isn’t all of it. Keep going.”

And there’s so much more. Listen to the entire conversation from this Insights At the Edge episode, “Waking Up: What Does It Really Mean?” 

E221: The True Meaning of Witness Consciousness

True witness consciousness is not willfully watching, analyzing, or trying to let go of thoughts and emotions; it is the effortless state of simply seeing whatever arises without touching it. There is a vast difference between passive “seeing” and intentional “looking.” If you catch a thought or emotion to decide whether it is good or bad, you are using your mind as a “gatekeeper” rather than experiencing true witness consciousness. As you evolve spiritually, thoughts, emotions, and other inner experiences simply pass through like writing on water, there is no need to touch them. You can reach this state when you are willing to go through life’s experiences. You become increasingly able to simply flow with life, serve what is in front of you, and eventually experience the deep spiritual state of liberated consciousness.

© Sounds True Inc. Episodes: © 2026 Michael A. Singer. All Rights Reserved.

Kimberly Ann Johnson: “Becoming a Sexual Alchemi...

What if aging isn’t the slow closing of your erotic life, but the doorway into its most alive season?

This week, Tami Simon speaks with Kimberly Ann Johnson—sexological body worker, somatic experiencing practitioner, birth doula, and author of the new Sounds True book Erotic Seasons: Tuning In to the Rhythms of Women’s Sexuality and Spirituality—about what she calls erotic sovereignty, and the sentence that closes her book: the female body is its own spiritual path.

Join Tami and Kimberly to explore:

  • Erotic sovereignty—your relationship to your own life force, and why it stays with you across every season
  • Why the goal isn’t a more regulated nervous system, but a more responsive one, and what it means to run more charge
  • The four erotic seasons—maiden, mother, virgin, crone—and the surprising reason virgin comes after mother
  • Why hormonal transitions are “wet clay”: golden opportunities for repatterning that our culture teaches us to rush past
  • Menopause as a death rehearsal, and the life review that arrives decades before we expect it
  • Hot sex and warm sex—widening the range beyond adrenaline, and learning the language of the pause
  • “Hormones are gods”: the collective endocrine system, and why living intergenerationally may be the original hormone therapy
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Whether you are 25 or 75, Kimberly offers a map for meeting your body’s changes as thresholds rather than losses.

Please note: this episode includes candid discussion of sexual abuse and sexual wounding, including Kimberly Ann Johnson’s own experience.

Listen now, and meet your body as the path. →

This conversation offers genuine transmission, not just concepts about awakening, but the palpable presence of realized teachers exploring the growing edge of spiritual understanding together, and it originally aired on Sounds True One.

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